Table 2

FICTION analysis
Case # Mutation Control CD30-) HR-S (CD30+) HR-S/ Control Predicted allele*
1 W 1.02 0.90 0.88 2
2 W 0.98 0.63 0.64 2
3 1487C>A (T474N) 0.99 0.71 0.72 2
4 W 1.11 0.80 0.72 2
5 W 1.11 0.54 0.49 1
6 W 1.06 0.14 0.13 0
7 W 0.94 0.65 0.69 2
8 W 0.96 0.45 0.47 1
9 W 1.01 0.64 0.63 2
10 W 0.97 0.77 0.79 2
11 W 1.02 0.81 0.79 2
12 ND 1.03 0.22 0.21 0
13 ND 0.99 0.93 0.94 2
14 ND 1.12 0.78 0.70 2
15 ND 1.04 0.83 0.80 2
16 ND 1.05 0.42 0.40 1
17 ND 1.19 1.07 0.90 2
18 ND 1.00 0.67 0.67 2
19 ND 1.17 0.50 0.43 1
20 ND 0.99 0.90 0.91 2
21 ND 0.95 0.21 0.22 0
22 ND 0.97 0.68 0.70 2
23 ND 0.93 0.71 0.76 2
24 ND 0.99 0.70 0.71 2
25 ND 1.00 0.82 0.82 2
26 ND 1.00 0.14 0.14 0
27 ND 1.02 0.32 0.31 1
28 ND 0.99 0.50 0.51 1
29 ND 0.99 0.41 0.41 1
30 ND 0.97 0.76 0.78 2
31 W 1.03 0.45 0.44 1
32 W 1.01 0.88 0.86 2
33 W 0.97 0.52 0.53 1
34 W 0.99 0.52 0.52 1
35 W 1.00 0.93 0.93 2
36 W 0.90 0.63 0.71 2
37 W 0.98 0.43 0.44 1
38 1777G>A (V571I) 1.04 0.72 0.69 2
39 W 1.06 1.00 0.94 2
40 1156A>G (R364G) 0.86 0.15 0.17 ND
41 W 0.91 0.19 0.21 0
42 W 0.89 0.31 0.35 ND
43 W 1.00 0.36 0.36 1
44 W 1.01 0.52 0.51 1
45 W 0.84 0.68 0.81 ND
46 569G>A (STOP) 0.99 0.69 0.70 2
47 W 1.00 0.45 0.45 1
3/25 (12%) Mean 1.01 Mean 0.61 Mean 0.60

* 0: homozygous, 5 cases; 1: heterozygous, 14 cases; 2: non deleted, 25 cases.

W, wild type; ND, not determined.

Cases #1-5 and #31-47 had been sequenced and reported elsewhere. Cases #6-11 were sequenced in this study. Cases #12-30 were not sequenced because of limited or poor quality DNA.

Nomoto et al.

Nomoto et al. BMC Cancer 2012 12:457   doi:10.1186/1471-2407-12-457

Open Data