Open Access Research article

Use of a chemically induced-colon carcinogenesis-prone Apc-mutant rat in a chemotherapeutic bioassay

Kazuto Yoshimi1, Takao Hashimoto2, Yusuke Niwa2, Kazuya Hata2, Tadao Serikawa1, Takuji Tanaka3 and Takashi Kuramoto1*

Author Affiliations

1 Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University, Yoshidakonoe-cho, Sakyo-ku, Kyoto 606-8501, Japan

2 Sunplanet Co., Ltd, 4388 Makita, Kamiishizu, Ogaki, 503-1602, Japan

3 Cancer Research and Prevention, The Tohkai Cytopathology Institute, 4-33 Minami-Uzura, Gifu, 500-8285, Japan

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BMC Cancer 2012, 12:448  doi:10.1186/1471-2407-12-448

Published: 3 October 2012

Additional files

Additional file 1:

Table S1. Number and total volume of tumors found in KAD rats at week 8.

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Additional file 2:

Figure S1. The correlation of total volume of tumors with the numbers of polypoid lesions observed by endoscopy at Week8. Regression formula was made with Excel software package (Microsoft). Vertical axis was shown in logarithmic scale.

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