Table 4

Objective response rate byworst skin toxicity grade
Objective response rate, %(95% CI)
WT KRAS MT KRAS Overalla
Grade 0/1(n= 16) Grade2+ (n= 69) Overall(n= 85) Grade0/1 (n= 19) Grade2+ (n= 39) Overall(n= 58) Grade0/1 (n= 35) Grade2+ (n= 117) Overall(n= 152)
37.5 (15.2, 64.6) 60.9 (48.4, 72.4) 56.5 (45.3, 67.2) 21.0 (6.0, 45.6) 46.2 (30.1, 62.8) 37.9 (25.5, 51.6) 28.6 (14,6, 46.3) 55.6 (46.1, 64.7) 49.3 (41.2, 57.6)

Objective response rate represents the proportion of patients with a best overall response of complete or partial response.

aAll patients in the tumour response analysis set regardless of KRAS evaluability.

Thaler et al.

Thaler et al. BMC Cancer 2012 12:438   doi:10.1186/1471-2407-12-438

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