Main networks obtained for the most relevant genes. These networks were generated through the use of Ingenuity Pathways Analysis www.ingenuity.com webcite. Genes are represented as nodes and the biological relationships between 2 nodes is represented as an edge (line). The functional analysis of the networks identified the biological functions and/or diseases that were most significant to the molecules in each network. In this sense, network 1 is associated to Cancer, Genetic disorder and Reproductive system disease; network 2 is associated to Free radical scavenging, Metabolic disease and Renal and Urological Disease; network 3 is associated to Post-translational Modifications, Protein folding and Cell death and network 4 is associated to Skeletal and Muscular System Development and Function, Tissue Development and Cell Death. Molecules in black represent the genes from our dataset. Dash lines represent indirect relationships (2000-2010 Ingenuity Systems, Inc).
García-Bilbao et al. BMC Cancer 2012 12:43 doi:10.1186/1471-2407-12-43