Schematic representations of Gemcitabine encapsulation into two biodegradable nanovectors. (A) PLGem is defined as Gemcitabine encapsulated in poly(lactic-co-glycolic) acid (PLGA) nanoparticles having a molecular weight of around 4.2 kDa by emulsion-evaporation technique. Magnification shows the predicted arrangement of Gemcitabine. (B) GemPo refers to Gemcitabine encapsulated in phosphatidylcholine-based liposomes using the lipid film hydration technique. Magnification shows the lipid bilayer.
Papa et al. BMC Cancer 2012 12:419 doi:10.1186/1471-2407-12-419