Figure 1.

Sanger sequencing validated a nonsense SDHA exon 2 p.Arg31X mutation in both tumor and normal DNA. The SDHA sequence electropherogram of the tumor DNA contained predominantly the mutated allele (T), indicating relative loss of the wild-type SDHA allele, compared to the normal DNA.

Italiano et al. BMC Cancer 2012 12:408   doi:10.1186/1471-2407-12-408
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