Table 3

*Adjusted ORs and 95% CI for the relationship between the C-peptide, IGFBP-1 and low apoptosis, among overweight and obese individuals (BMI > 30)
Overall Men Women
Measure
    Apoptosis (n, Lower/upper half)
Adjusted OR1(95% CI)
    Apoptosis (n, Lower/upper half)
Adjusted OR1(95% CI)
    Apoptosis (n, Lower/upper half)
Adjusted OR1(95% CI)
C-Peptide
Quartile 1 12/16 1.0 (Referent) 6/7 1.0 (Referent) 6/9 1.0 (Referent)
Quartile 2 26/20 3.1 (1.0, 9.5) 9/11 4.4 (0.7, 30.0) 17/9 3.9 (0.9, 16.1)
Quartile 3 33/24 2.7 (0.9, 8.1) 17/9 7.0 (1.1,45.3) 16/15 1.9 (0.5, 7.3)
Quartile 4 54/45 2.5 (0.9, 7.1) 30/21 6.3 (1.1, 36.7) 24/24 1.5 (0.4, 5.5)
P trend 0.0465 0.04 0.30
IGFBP-1
Quartile 1 51/35 1.0 (Referent) 24/13 1.0 (Referent) 27/22 1.0 (Referent)
Quartile 2 44/33 0.9 (0.5, 1.9) 23/16 0.9 (0.3, 2.6) 21/17 1.0 (0.4, 2.5)
Quartile 3 22/19 0.9 (0.4, 2.1) 12/12 0.5 (0.1, 1.6) 10/7 1.4 (0.4, 4.9)
Quartile 4 8/18 0.3 (0.1, 1.0) 3/7 0.2 (0.03, 1.2) 5/11 0.4 (0.1, 1.5)
P trend 0.10 0.07 0.44
Insulin
Quartile 1 11/14 1.0 (Referent) 6/8 1.0 (Referent) 5/6 1.0 (Referent)
Quartile 2 25/17 1.6 (0.5, 5.1) 16/5 2.3 (0.4, 13.1) 9/12 1.1 (0.2, 5.5)
Quartile 3 33/25 1.3 (0.4, 3.9) 17/13 0.7 (0.1, 3.4) 16/12 1.7 (0.3, 8.5)
Quartile 4 40/32 1.5 (0.5, 4.4) 17/10 1.0 (0.2, 4.9) 23/22 1.6 (0.4, 7.1)
P trend 0.46 0.99 0.53

*Adjusted for race, sex, alcohol intake, diabetes history, smoking and red meat intake.

Vidal et al.

Vidal et al. BMC Cancer 2012 12:389   doi:10.1186/1471-2407-12-389

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