Table 2

Adjusted geometric means and 95% CI of CRP and SAA stratified by obesity status at 24-month follow-up assessment (n = 134)
Stratifying variablea CRP Mean (95%CI) SAA Mean (95%CI)
Not obese (N = 39) Obeseb(N = 95) Not obese (N = 39) Obese (N = 95)
Overall 0.85 (0.61-1.20)1 2.01 (1.64-2.46)2 4.21 (3.34-5.30)1 6.21 (5.42-7.11)2
NSAID usec
No (n = 31/55)d 0.84 (0.58-1.21)1 2.31 (1.78-3.00)2 4.29 (3.36-5.48)1 7.24 (6.13-8.56)2
Yes (n = 8/40) 0.99 (0.49-1.97)1,2 1.64 (1.20-2.23)1,2 4.59 (2.93-7.19)1,2 4.87 (3.95-6.00)1
History of arthritis
No (n = 34/45) 0.81 (0.57-1.17)1 1.89 (1.41-2.52)2 3.70 (2.93-4.67)1 5.37 (4.46-6.47)1,2
Yes (n = 5/50) 0.91 (0.38-2.18)1,2 2.19 (1.65-2.90)2 4.06 (2.31-7.16)1,2 7.75 (6.46-9.31)2
Weight Changee
Loss (n = 7/5) 0.75 (0.36-1.57)1,2 1.96 (0.81-4.78)1,2 3.11 (1.94-4.98)1 5.27 (2.97-9.35)1,2
No Change (n = 22/66) 0.70 (0.46-1.07)1 1.93 (1.51-2.47)2 4.28 (3.23-5.67)1,2 5.88 (4.99-6.92)1,2
Gain (n = 10/24) 1.12 (0.59-2.12)1,2 2.50 (1.69-3.69)2 4.51 (2.97-6.86)1,2 7.81 (6.07-10.04)2

a Scheffé multiple comparison procedure (p < .05) was used to compare differences across groups. For each variable means with different numbers (1-3) are statistically different form one another and evaluated separately for CRP and SAA.

CRP means are adjusted for age, race/ethnicity, energy (kcal), NSAID (yes/no), and weight difference (kg), SAA means are additionally adjusted for arthritis (yes/no).

b Obese ≥35% Body Fat, not obese < 35% Body Fat.

c Current use of over-the-counter or prescription non-steroidal ant-inflammatory drugs (NSAID). Adjusted for age, ethnicity, energy (kcal), weight difference (kg).

d Sample size (n) represents number of non-obese and obese women in each stratum. e.g. 31 non-obese and 35 obese women who are non-users of NSAID. The same formatting in describing sample size is used for other strata.

e Adjusted for age, ethnicity, energy (kcal), NSAID (yes/no). Weight gain is >5% increase in bodyweight since baseline and weight loss is >5% decrease since baseline.

Dee et al.

Dee et al. BMC Cancer 2012 12:343   doi:10.1186/1471-2407-12-343

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