Table 2

Univariate and multivariate Cox regression analysis of overall survival among patients AM-RCC who underwent nephrectomy of any kind (n = 81)
Parameter Univariate Multivariate
n P HR 95% CI P HR 95% CI
Age, yr
<62.0 39 1.00 1.00
≥62.0 42 0.026 1.87 1.08−3.26 0.177 1.51 0.083−2.76
Sex
Female 25 1.00 X
Male 56 0.840 0.94 0.53-1.68
ECOG PS
0 44 1.00 1.00
1 32 0.001 2.54 1.45-4.34 0.012 2.22 1.19-4.16
≥2 5 0.000 7.89 2.56-24.3 0.022 4.18 1.23-14.3
Hb
≥Lower normal limit 45 1.00 1.00
<Lower normal limit 36 0.047 1.72 1.01-2.92 0.862 1.06 0.58-1.93
LDH
≦Normal limit × 1.5 51 1.00 x
>Normal limit × 1.5 30 0.567 1.17 0.69-2.00
ALP
≦Normal limit × 1.5 78 1.00 1.00
>Normal limit × 1.5 3 0.026 3.92 1.18-13.0 0.510 0.60 0.13-2.76
Corrected Ca, mg/dL
<10.0 50 1.00 x
≥10.0 31 0.404 0.79 0.45-138
Max. tumor diameter, cm
<8.0 41 1.00 x
≥8.0 40 0.381 0.78 0.45-1.35
No. of metastatic organ sites
0,1 35 1.00
≥2 46 0.054 1.72 0.99-2.99 0.011 2.33 1.21-4.48
CRP, mg/L
≦18.0 49 1.00 1.00
>18.0, <67. 20 0.057 1.86 0.98-3.54 0.036 2.06 1.05-4.05
0 ≥ 67.0 12 0.000 6.66 3.16-14.01 0.001 5.85 2.07-16.56

*X, excluded from the multivariate analysis.

Ito et al.

Ito et al. BMC Cancer 2012 12:337   doi:10.1186/1471-2407-12-337

Open Data