Consort Diagram outlining patient selection criteria for the OSCC study cohort. Sufficient tumour tissue for TMA construction was available for 69 patients. TMA cores from 64 patients were included in the analysis of Bax expression; TMA cores from 63 patients were analyzed for Bcl-2 and Bcl-XL expression. The same 63 patients were consistent between Bax, Bcl-2 and Bcl-XL expression analyses. The loss of 5 patients (Bax expression analysis) and 6 patients (Bcl-2 and Bcl-XL expression analysis) was due to the insufficient tumour, core loss during sectioning, or folding of the tissue in all three cores of a particular patient.
Bose et al. BMC Cancer 2012 12:332 doi:10.1186/1471-2407-12-332