Open Access Research article

Bax expression measured by AQUAnalysis is an independent prognostic marker in oral squamous cell carcinoma

Pinaki Bose1, Alexander C Klimowicz2, Elizabeth Kornaga2, Stephanie K Petrillo2, T Wayne Matthews3, Shamir Chandarana3, Anthony M Magliocco25, Nigel T Brockton4 and Joseph C Dort3*

Author Affiliations

1 Department of Oncology, University of Calgary, Calgary, Canada

2 Department of Oncology, University of Calgary, Calgary, Canada

3 Division of Otolaryngology-Head and Neck Surgery, University of Calgary, Calgary, Canada

4 Department of Population Health Research, Alberta Health Services – Cancer Care, Calgary, Canada

5 Present Address: H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, Tampa, FL, 33612, USA

For all author emails, please log on.

BMC Cancer 2012, 12:332  doi:10.1186/1471-2407-12-332

Published: 1 August 2012

Additional files

Additional file 1:

Figure S1. Kaplan-Meier survival analysis of Ki67 expression. Kaplan-Meier survival curves and corresponding risk tables for 5 year disease-specific survival in OSCC patients with below median or above median Ki67.

Format: TIFF Size: 173KB Download file

Open Data

Additional file 2:

Figure S2. Kaplan-Meier survival analysis of ratios between pro-apoptotic and anti-apoptotic Bcl-2 family proteins. Kaplan-Meier survival curves and corresponding risk tables for 5 year disease-specific survival in OSCC patients with below median or above median (A) Bcl-2/Bax and (B) Bcl-XL/Bax. Cut-points were selected at median.

Format: TIFF Size: 230KB Download file

Open Data

Additional file 3:

Figure S3. Kaplan-Meier survival analysis of Bax expression with respect to treatment in OSCC. Kaplan-Meier curves for 5-year disease-specific survival using (A) Bax expression for patients treated with surgery and post-operative radiation and (B) Bax expression for patients treated with surgery only (no radiation). Cut-points were selected at median.

Format: TIFF Size: 218KB Download file

Open Data