Table 1

Dose and fractionations by site
Tumor Location Description Total Dose (Gy) Number of fractions Dose per fraction (Gy) Frequency
Lung Tumors 3 cm or less surrounded by lung parenchyma 54 3 18 Every second day
Abutting chest wall or >3 cm 55 5 11 Every second day
Within 2 cm of mediastinum or brachial plexus 60 8* 7.5 Every second day
Bone Any bone except femur 35 Gy 5 7 Daily
Vertebral body: additional options 16-20 Gy OR 1 16-20 Single dose
30 Gy 3 10 Every second day
Brain Metastases If whole brain treated, then simultaneous boost to each lesion 40 Gy to metastases 20 Gy whole brain (optional) 5 8 Gy to lesion 4 Gy WBRT Daily
Liver LRCP site: Dose is based on calculated normal tissue probability of <5% Every second day
Other sites 45-60 3-8 7.5-15 Every second day
Adrenal 60 Gy 8 7.5 Every second day

*If esophageal dose constraints cannot be met, 12 fractions should be used.

Palma et al.

Palma et al. BMC Cancer 2012 12:305   doi:10.1186/1471-2407-12-305

Open Data