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Different fatty acid metabolism effects of (−)-Epigallocatechin-3-Gallate and C75 in Adenocarcinoma lung cancer

Joana Relat1, Adriana Blancafort2, Glòria Oliveras23, Sílvia Cufí3, Diego Haro1, Pedro F Marrero1 and Teresa Puig2*

Author Affiliations

1 Biochemistry and Molecular Biology, School of Pharmacy and Institute of Biomedicine of the University of Barcelona (IBUB), 08028, Barcelona, Spain

2 Molecular Oncology (NEOMA), School of Medicine, University of Girona and Girona Institute for Biomedical Research (IDIBGi), 17071, Girona, Spain

3 Molecular Oncology, Catalan Institute of Oncology (ICO), Girona Institute for Biomedical Research (IDIBGi), 17007, Girona, Spain

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BMC Cancer 2012, 12:280  doi:10.1186/1471-2407-12-280

Published: 6 July 2012

Additional files

Additional file 1 :

Figure S1. EGCG and C75 show cytotoxic activity in A549 human lung carcinoma cells. A549 cells were treated with different concentrations of C75 (20 – 200 μM) or EGCG (40 – 300 μM) for 48 hours. Pale gray (●) and dark grey (●) circles represent the percentage of A549 cell proliferation inhibition after C75 and EGCG treatment respectively, which was determined using an MTT assay. Results are expressed as mean percentage of inhibition in cell proliferation from three independent experiments performed in triplicate ± SE. PDF File Format.

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