Open Access Research article

The database of chromosome imbalance regions and genes resided in lung cancer from Asian and Caucasian identified by array-comparative genomic hybridization

Fang-Yi Lo1, Jer-Wei Chang1, I-Shou Chang2, Yann-Jang Chen3, Han-Shui Hsu4, Shiu-Feng Kathy Huang5, Fang-Yu Tsai2, Shih Sheng Jiang2, Rajani Kanteti6, Suvobroto Nandi6, Ravi Salgia6 and Yi-Ching Wang1*

Author Affiliations

1 Department of Pharmacology and Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, No.1, University Road, Tainan 701, Taiwan

2 Institute of Cancer Research, National Health Research Institutes, Miaoli, Taiwan

3 Department of Life Sciences and Institute of Genome Sciences, National Yang Ming University, Taipei, Taiwan

4 Institute of Emergency and Critical Care Medicine, National Yang Ming University and Division of Thoracic Surgery, Taipei Veterans General Hospital, Taipei, Taiwan

5 Division of Molecular and Genomic Medicine, National Health Research Institutes, Miaoli, Taiwan

6 Department of Medicine, Cancer Research Center, The University of Chicago Medical Center, Pritzker School of Medicine, Chicago, IL, USA

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BMC Cancer 2012, 12:235  doi:10.1186/1471-2407-12-235

Published: 12 June 2012

Additional files

Additional file 1:

Table S1.Overall list of lung cancer patient in array-CGH, and candidate gene validations.

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Additional file 2:

Table S2.The selected 18 chromosome regions investigated in the current array-CGH study.

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Additional file 3:

Figure S1.Array image and schematic illustrations of the Bayes regression approach for identifying the regions with chromosomal copy number changes.

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Additional file 4:

Table S3.Primers and PCR conditions used in the current study.

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Additional file 5:

Table S4.List of candidate genes in Asian and Caucasian lung cancer patients.

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Additional file 6:

Table S5.Association between mRNA expression level and lung cancer clinicopathological parameters of four candidate genes in Asian.

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