Open Access Highly Accessed Research article

ERLIN2 promotes breast cancer cell survival by modulating endoplasmic reticulum stress pathways

Guohui Wang128, Gang Liu1, Xiaogang Wang1, Seema Sethi36, Rouba Ali-Fehmi4, Judith Abrams37, Ze Zheng2, Kezhong Zhang125*, Stephen Ethier19 and Zeng-Quan Yang13*

Author Affiliations

1 Karmanos Cancer Institute, Wayne State University, Detroit, MI, 48201, USA

2 Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, 48201, USA

3 Department of Oncology, Wayne State University, Detroit, MI, 48201, USA

4 Department of Pathology, Wayne State University, Detroit, MI, 48201, USA

5 Department of Immunology and Microbiology, Wayne State University, Detroit, MI, 48201, USA

6 Biorepository Core, Wayne State University, Detroit, MI, 48201, USA

7 Biostatistics Core of the Karmanos Cancer Institute, Wayne State University, Detroit, MI, 48201, USA

8 Department of Medical Imaging and Interventional Radiology, State Key Laboratory of Oncology in South China, Cancer Center, Sun Yat-Sen University, No. 651, Dongfeng Road East, Guangzhou, 510060, China

9 Department of Pathology and Laboratory Medicine, Hollings Cancer Center, Medical University of South Carolina, BEB 412, 68 President St, Charleston, SC 29425, USA

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BMC Cancer 2012, 12:225  doi:10.1186/1471-2407-12-225

Published: 8 June 2012

Additional files

Additional file 1:

Materials and Methods[54-58].

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Additional file 2: Table S1:

Expression Levels of XBP1, ERLIN1 and ERLIN2 in Ten SUM BreastCancer Cell Lines Using Our Affymetrix Array Database. Table S2: Expression of ERLIN2 in breast tissues:carcinomas and normal. Figure S1. Figure S2. Figure S3. Figure S4. Figure S5.

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