Table 2

Follicular Lymphoma International Prognostic Index (FLIPI) and Follicular Lymphoma International Prognostic Index 2 (FLIPI 2)
FLIPI
Risk factors
· Age <60 years vs. ≥60 years
· Hemoglobin ≥12 g/dL vs. <12 g/dL
· Serum LDH ≤ ULN vs. >ULN*
· Ann Arbor stage I-II vs. III-IV
· No. of nodal sites ≤4 vs. >4
Risk group No. of factors 5–year OS** 10–year OS** Relative risk
Good 0–1 91% 71% 1
Intermediate 2 78% 51% 2.3
Poor ≥3 53% 36% 4.3
FLIPI 2
Risk factors
· Beta-2-microglobulin > ULN*
· Longest diameter of the largest involved node > 6 cm
· Bone marrow involvement
· Hemoglobin level < 12 gr/L
· Age older than 60 years
Risk group No. of factors 3-year PFS*** 5-year PFS*** Relative risk
Low 0 90.9% 79.5% 1
Intermediate 1-2 69.3% 51.2% 3.19
High 3-5 51.3% 18.8% 5.76

* ULN: under limits normal.

** OS: overall survival.

*** PFS: progression free survival.

Rueda et al.

Rueda et al. BMC Cancer 2012 12:210   doi:10.1186/1471-2407-12-210

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