Table 3

Genes linked to genomic instability
Biological Process Gene Symbol Gene Name Contrast log2 (Fold Change)
DNA damage response and repair downregulation EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 A1789TvsWT −0.4309041
SMC1A structural maintenance of chromosomes 1A A1789TvsWT MutvsWT

−0.2754507

−0.2640263

PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme A1789TvsWT −0.4286825
AHNAK AHNAK nucleoprotein A1789TvsWT M1775RvsWT MutvsWT −0.3988113
−0.3103867
−0.3940570
SOD2 superoxide dismutase 2, mitochondrial M1775RvsWT MutvsWT −0.3376169
−0.2502831
DNA damage response and repair upregulation MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) A1789TvsWT 0.3293561
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 MutvsWT 0.2790907
OBFC2A oligonucleotide/oligosaccharide-binding fold containing 2A M1775RvsWT 0.3666172
OBFC2B oligonucleotide/oligosaccharide-binding fold containing 2B A1789TvsWT MutvsWT 0.4070777
0.3417360

Iofrida et al.

Iofrida et al. BMC Cancer 2012 12:207   doi:10.1186/1471-2407-12-207

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