Table 5

Compared clinicalpathological features between 35 surgical HCC patients with multiple primary tumor and 140 HCC patients without extrahepatic tumor
Characteristic

Multiple primary

tumor group (n=35)

Control group

(HCC-alone) (n=140)

P value
Age (years) * 56.3±12.6 59.1±11.2 0.317
Gender (Female: Male) 5:30 30:115 0.616
HBsAg (Negative: Positive) 7:28 12:128 0.101
AFP level (<25: ≥25) (ng/ml) 17:18 44:96 0.057
GGT level (<50: ≥50) (U/ml) 11:24 53:87 0.480
Child-Pugh classification (A:B) 32:3 134:6 0.549
Tumor size (<5cm : ≥5cm) 12:23 40:100 0.508
Tumor number (Solitary: Multiply) 30:5 132:8 0.171
Vascular invasion (No: Yes) 32:3 131:9 0.940
Tumor capsule (No: Yes) 19:16 60:80 0.224
Cirrhosis (No: Yes) 8:27 23:117 0.373
Surgical margin (<2cm : ≥2cm) 20:15 57:83 0.080
TNM stage (I: II: III) 26:4:5 112:18:10 0.401
Complication (No: Yes) 6:29 14:126 0.373

HCC: hepatocellular carcinoma, HBsAg: hepatitis B surface antigen, AFP: α-fetoprotein, GGT: gamma-glutamyltransferase, TNM: tumor-node-metastasis.

* Mean ± Standard Deviation.

Chi-square test for difference between proportions (except that of Age).

T test for difference between means.

Zeng et al.

Zeng et al. BMC Cancer 2012 12:148   doi:10.1186/1471-2407-12-148

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