Table 2

Correlations between ALCAM expression and clinicopathological factors

ALCAM expression

All patients

negative (IRS 0-1)

positive (IRS 2-12)

p-value

All samples

233

97

136

Histological subtype (n = 233)

squamous

171

70

101

adenomatous

35

18

17

adenosquamous

27

9

18

0.338

FIGO stage (n = 233)

I

143

60

83

II

65

25

40

III/IV

25

12

13

0.971

Nodal

involvement (n = 233)

pN0

175

75

100

pN1

58

22

36

0.542

Number of Positive lymph nodes (n = 233)

0

175

75

100

1-3

39

12

27

> 3

19

10

9

0.229

Tumor grade

(n = 227)

G1

9

4

5

G2

100

43

57

G3

118

46

72

0.788

Lymphatic invasion (n = 207)

L0

68

33

35

L1

139

55

84

0.234

Invasion depth in mm (n = 195)

geometric mean

14.2

14.3 (n = 90)

14.1 (n = 105)

0.856

Patients age in years (n = 233)

mean

48.8

48.3

49.1

0.662

SCC-Ag in μg/L (n = 156)

geometric mean

1.9

2.5 (n = 64)

1.5 (n = 92)

0.012

s-ALCAM in ng/mL (n = 55)

geometric mean

28.3

29.0 (n = 21)

27.8 (n = 34)

0.515

Progression-free survival in months (PFS; n = 47)

median

13

9 (n = 19)

15 (n = 28)

0.208

Ihnen et al. BMC Cancer 2012 12:140   doi:10.1186/1471-2407-12-140