The clinical significance of tumor infiltrating lymphoctyes in breast cancer: does subtype matter?
Department of Surgery and Cancer, Imperial College, Hammersmith Hospital, Du Cane Road, London W12 ONN, UK
BMC Cancer 2012, 12:135 doi:10.1186/1471-2407-12-135Published: 3 April 2012
Tumor infiltrating lymphocytes (TILs) are commonly detected in breast tumors but their bearing on disease outcome is uncertain. The importance of TILs appears to be subtype-specific and varies depending on the histologic characteristics of the tumor. As our understanding of tumorigenesis is increasing the relevance of immunobiology will become apparent.