JS-K diminishes WNT-signalling in 22Rv1 cells. 22Rv1 cells were co-transfected with an expression vector for mutated, stabilized β-catenin together with either the TCF reporter construct TOP or FOP as recently described . Data are presented as fold of untreated controls (TOP/FOP) ± SD, **p < 0.01, ***p < 0.001.
Laschak et al. BMC Cancer 2012 12:130 doi:10.1186/1471-2407-12-130