CD24+/ALDH1+/CD44high identifies a population of TICs in both TNBC and TPBC cell fractions. The log-fraction plot of the limiting dilution model has been generated using ELDA software for limiting dilution analysis (LDA) after fitting the data from Table 1. The slopes for CD24+/ALDH1+/CD44high cells derived from TNBC (green line), CD24+/ALDH1-/CD44low cells derived from TNBC (blue line), CD24+/ALDH1+/CD44high cells derived from TPBC (black line), CD24+/ALDH1-/CD44low cells derived from TPBC (red line), is the log-active cell fraction. The dotted lines give the 95% confidence interval.
Kaur et al. BMC Cancer 2012 12:120 doi:10.1186/1471-2407-12-120