Modulation of TRAIL resistance in colon carcinoma cells: Different contributions of DR4 and DR5
- Equal contributors
1 Departments of Medical Oncology and Gastroenterology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands
2 Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands
BMC Cancer 2011, 11:39 doi:10.1186/1471-2407-11-39Published: 27 January 2011
Additional file 1:
Effects of IFN-γ on c-FLIP cleavage. Western blot analysis of c-FLIP levels in SW948-TR after 48 h preincubation with 1000 U/ml IFN-γ in combination with rhTRAIL (0.1 μg/ml), agonistic DR4 or DR5 antibody (50 nM) treatment for 5 h.
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