Table 1

Characteristics of breast cancer in less than 40 yrs women compared to more than 40 yrs group

Variable

Less than 40

(n = 276)

More than 40

(N = 2869)

P Value


Age in yrs (SD) #

< 0.001*

Mean

35.81 (3.92)

60.08 (12.22)

Median (range)

37 (20-40)

59 (41-96)


Tumour size (mm) #

0.477

Mean

21.49

22.74

Median (range)

20 (1-120)

20 (1-160)


Tumour grade

0.044*

Grade 0

69 (27%)

697 (26.47%)

Grade 1

23 (9%)

262 (9.9%)

Grade 2

70 (27.3%)

912 (34.5%)

Grade 3

94 (36.7%)

774 (29.3%)


Histology Type

< 0.001*

Ductal

178 (74.2%)

1768 (72.8%)

Lobular

18 (7.5%)

368 (15.2%)

Others

44 (18.3%)

291(12%)


Tumour stage

0.046*

0

17 (7.4%)

210 (9.2%)

I

66 (28.6%)

538(23.6%)

II

93 (40.3%)

850 (37.3%)

III

46 (19.9%)

477 (20.9%)

IV

9 (3.9%)

202 (8.9%)


ER status

< 0.001*

Positive

123 (58.3%)

1629 (74.5%)

Negative

88 (41.7%)

559 (25.5%)


PR status

0.319

Positive

102 (70.3%)

1142 (72.5%)

Negative

43 (29.7%)

433 (27.5%)


Her-2 status

0.002*

Positive

34 (30.6%)

213 (18.6%)

Negative

77 (69.4%)

935 (81.4%)


Surgical treatment

< 0.001*

Mastectomy

192 (75.9%)

1647 (61.9%)

BCS

61 (24.1%)

1012 (38.1%)


Adjuvant hormonal therapy

0.005*

Yes

184 (86.4%)

2924 (92.4%)

No

29 (13.6%)

159(7.6%)


Adjuvant chemotherapy

0.021*

Yes

109 (46.2%)

866 (38.4%)

No

127 (53.8%)

1389 (61.6%)


Adjuvant radiotherapy

0.778

Yes

135 (59.2%)

1234 (58%)

No

93 (40.8%)

892 (42%)


# Mann-Whitney u test, ER = Estrogens receptor, PR = Progesterone receptor

Kheirelseid et al. BMC Cancer 2011 11:383   doi:10.1186/1471-2407-11-383

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