Table 3

ORs of breast cancer associated with intake of dietary antioxidants, NECSS, Canada, 1994-1997

Pre-menopausal

Post-menopausal



Nutrient

Quartiles of intake

Quartiles of intake

Q1*

Q2

Q3

Q4

p for

Q1*

Q2

Q3

Q4

p for

OR† (95% CI)

OR† (95% CI)

OR† (95% CI)

trend

OR†† (95% CI)

OR†† (95% CI)

OR†† (95% CI)

trend


Carotenoids

Beta-carotene (μg/wk)#

1.00

0.87 (0.65-1.15)

0.97 (0.73-1.28)

0.87 (0.65-1.17)

0.55

1.00

0.89 (0.72-1.10)

0.84 (0.68-1.04)

0.85 (0.68-1.06)

0.13

Alpha-carotene (μg/wk)

1.00

0.82 (0.61-1.10)

0.95 (0.72-1.25)

0.85 (0.64-1.14)

0.46

1.00

0.86 (0.72-1.11)

0.89 (0.71-1.12)

0.92 (0.73-1.14)

0.53

Lycopene (μg/wk)

1.00

0.97 (0.74-1.28)

0.99 (0.76-1.31)

0.88 (0.65-1.20)

0.53

1.00

1.15 (0.93-1.43)

1.20 (0.97-1.49)

1.21 (0.96-1.51)

0.14

Lutein and Zeaxanthin (μg/wk)

1.00

0.92 (0.69-1.23)

1.08 (0.82-1.44)

0.82 (0.61-1.11)

0.41

1.00

0.81 (0.64-1.02)

0.94 (0.75-1.19)

0.94 (0.74-1.19)

0.86

Beta cryptozanthin (μg/wk)

1.00

1.20 (0.89-1.60)

1.15 (0.87-1.53)

1.18 (0.86-1.60)

0.38

1.00

1.21 (0.98-1.50)

1.13 (0.90-1.40)

1.31 (1.04-1.65)

0.05

Vitamin C (mg/wk) #

1.00

1.00 (0.75-1.35)

1.21 (0.92-1.61)

0.87 (0.64-1.20)

0.89

1.00

1.13 (0.91-1.40)

1.14 (0.91-1.42)

1.24 (0.98-1.56)

0.09

Vitamin E (mg/wk) #

1.00

1.26 (0.93-1.70)

1.22 (0.89-1.68)

0.88 (0.62-1.25)

0.43

1.00

0.93 (0.75-1.15)

0.93 (0.74-1.17)

0.92 (0.73-1.17)

0.54

Selenium (μg/wk) #

1.00

1.22 (0.91-1.63)

1.23 (0.90-1.68)

1.10 (0.75-1.61)

0.58

1.00

1.21 (0.99-1.53)

1.10 (0.88-1.39)

1.09 (0.84-1.43)

0.73

Zinc (mg/wk) #

1.00

1.05 (0.78-1.41)

1.14 (0.83-1.57)

1.18 (0.79-1.77)

0.35

1.00

1.07 (0.85-1.35)

1.07 (0.84-1.36)

1.21 (0.91-1.71)

0.23


* Reference category

† Adjusted for age, province of residence, education, smoking pack years, alcohol consumption, number of live births, age at menarche, and total energy intake.

†† Adjusted for age, province of residence, education, smoking pack years, alcohol consumption, BMI, recreational physical activity, number of live births, age at menarche, and total energy intake.

# Also adjusted for years of taking antioxidants from supplementation.

Pan et al. BMC Cancer 2011 11:372   doi:10.1186/1471-2407-11-372

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