Table 2

Disease specific- survival analysis at 24 years follow-up

Variable

n

HR (95%CI)

p (univariate)

HR (95%CI)

p (multivariate)


ER > 10%

118

0.41 (0.24-0.72)

0.0018*

PR > 10%

118

0.71 (0.40-1.25)

0.2322

Ki-67 > 15%

117

2.35 (1.34-4.13)

0.0030*

2.01 (1.12-3.59)

0.0186*

Bcl-2 > 25%

118

0.33 (0.18-0.63)

0.0007*

0.45 (0.23-0.86)

0.0158*

Triple-neg

118

2.05 (1.15-3.68)

0.0158*

Basal-type

118

2.34 (1.20-4.58)

0.0127*

p53 > 10%

118

1.73 (0.98-3.06)

0.0601

MMP-1 tumour cells > 70%

118

1.99 (1.12-3.53)

0.0194*

1.81 (1.01-3.22)

0.0438*

MMP-1 fibroblasts > 30%

118

1.35 (0.77-2.39)

0.2948


HR = Hazard Ratio

P-value less than 0.05 (*) were considered as significant.

Tumour grade was not included in disease specific -survival analysis, because none of grade I patients died of breast cancer.

Boström et al. BMC Cancer 2011 11:348   doi:10.1186/1471-2407-11-348

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