Table 4

Murine serum IGF-1 concentrations during the ketogenic diet

days post tumor cell implantation


14

24

38

65-115


control

KD

control

KD

control

KD

control

KD


animals

4

4

3

3

3

3

10

9


IGF-1 [ng/mL]

245.0

± 50.3

310.3

± 36.8

310.0

± 28.9

417.5

± 106.1

312.7

± 84.9

301.9

± 36.5

242.8

± 53.2

292.2

± 58.1


After LNT-229 tumor cell implantation at day 0, animals were randomized into two diet groups, a standard diet versus a ketogenic diet (day 1). On days 14, 24 and 38 as well as at the end of the experiment (days 65-115), serum was obtained by centrifugation of whole blood at 2000 g for 10 min and subsequently stored at -80°C. Murine IGF-1 serum levels determined by immunoassay were not significantly different between diet groups (KD, ketogenic diet; mean and standard deviation).

Maurer et al. BMC Cancer 2011 11:315   doi:10.1186/1471-2407-11-315

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