Table 2 

Nottingham Prognostic Index components on triplenegative and nontriplenegative breast cancer subtypes 

Nottingham Prognostic Index Components 

Molecular Subtype 
Tumour Size Mean ± St. Error 
Tumour Grade 
Lymph Node Status 

I 
II 
III 
None 
1 < LNS < 3 
LNS > 3 



Luminal 
2.92 cm ± 0.105 
24.1% 
38% 
38% 
43.9% 
26.7% 
29.4% 

(N = 302) 
(N = 324) 
(N = 262) 

HEROE 
3.08 cm ± 0.203 
4.9% 
16.5% 
78.6% 
42.4% 
24.2% 
33.3% 

(N = 93) 
(N = 103) 
(N = 99) 

Triple Negative (TNBC) 
3.70 cm ± 0.211 
4.9% 
23.9% 
71.2% 
48.6% 
25% 
26.4% 

(N = 155) 
(N = 163) 
(N = 148) 



Luminal 
Pvalue* 

Statistics 
TNBC vs 
p < 0.001 
Pvalue** < 0.0001 
Pvalue** Not significant 

HER2OE 
P = 0.05 



*ANOVA was used to compare the means of the three groups ** Pvalues were calculated with the use of the χ^{2 }test 

Albergaria et al. BMC Cancer 2011 11:299 doi:10.1186/1471240711299 