Significance of the NPI components to breast cancer mortality risk and survival in TNBC patients. Kaplan-Meier survival curves for tumour size (A) and for lymph node status (B). Both NPI components are highly statistically relevant to predict long term survival in TNBC patients; (C) Hazard ratio (CI 95%) in the TNBC cohort was calculated for tumour size and lymph node status. Patients with triple-negative tumours larger than 5 cm display a 3.2-fold risk of death by breast cancer; Concerning axillary lymph node status, TNBC patients with lymphatic involvement higher than 3 nodes have a 4.5-fold risk of breast-cancer specific death.
Albergaria et al. BMC Cancer 2011 11:299 doi:10.1186/1471-2407-11-299