Table 2

Clinicopathological variables and their correlation with immunohistochemical expression of HER-2/neu and VEGF

Variable

Patients

HER-2/neu

P-valuea

VEGF

P-valuea



Positive

Negativ

Positive

Negative


Sex

0.553

0.438

Male

187

29

158

105

82

Female

130

20

110

71

59

Age

0.525

0.817

≤60

195

28

167

107

88

> 60

122

21

101

69

53

Tumor size (cm)

0.004

0.000

< 5 cm

211

23

183

95

111

≥ 5 cm

106

26

85

81

30

Differentiation grade

0.193

0.451

Well

90

10

80

55

35

Moderate

152

23

129

81

71

Poor

75

16

59

40

35

T stage

0.166

0.177

T1~T2

97

11

86

48

49

T3~T4

220

38

182

128

92

Lymph node status

0.460

0.119

Negative

167

25

142

87

80

Positive

150

24

126

89

61

Distant metastasis

0.010b

0.017

M0

291

40

251

156

135

M1

26

9

17

20

6

Perineural invasion

0.127b

0.232

Negative

299

44

255

168

131

Positive

18

5

13

8

10


a Pearson χ2 test

b Adjusted χ2 test

Li et al. BMC Cancer 2011 11:277   doi:10.1186/1471-2407-11-277

Open Data