Effect of Flaxseed (FS) diet on body weight of mice 4 months post-XRT. Mice were fed with 0% or 10%FS diet prior (-3 weeks) or post (+2, +4, +6 weeks) X-ray radiation therapy (XRT). Body weight was recorded at 4 months post-irradiation. Data is represented mean ± SEM of two independent experiments (n = 15-25 mice per group). The white, black, gray and hatched bars represent untreated control, 0%FS + XRT, 10%FS and 10%FS + XRT groups, respectively. The dotted line represents weight average in non-irradiated control animals. *p ≤ 0.01 for irradiated 0%FS vs. irradiated 10%FS, $p ≤0.01 for irradiated vs. non-irradiated 0% and #p ≤ 0.05 irradiated 10%FS (initiated 3 weeks prior to XRT) vs. all irradiated 10%FS (diet initiated on, or post-XRT).
Christofidou-Solomidou et al. BMC Cancer 2011 11:269 doi:10.1186/1471-2407-11-269