Table 2

Association of E-cadherin with tumour stage, differentiation grade and lymph node status

Cadherin low (IRS ≤ 9)

n = 79 (65.8%)

Cadherin high (IRS > 9)

n = 41 (34.2%)

P-value


Tumor stage

0.4451)

pT1

40 (50.6%)

24 (58.5%)

pT2

39 (49.4%)

17 (41.5%)

Differentiation grade*

0.0182)

Grade I (well)

7 (9.5%)

7 (18.4%)

Grade II (moderate)

51 (68.9%)

29 (76.3%)

Grade III (poor)

16 (21.6%)

2 (5.3%)

Sentinel node

0.0051)

negative

42 (53.2%)

33 (80.5%)

positive

37 (46.8%)

8 (19.5%)


*Eight patients with differentiation grade not otherwise specified have been excluded

1) Fisher's exact test, 2) exact Mann-Whithey U test

Huber et al. BMC Cancer 2011 11:217   doi:10.1186/1471-2407-11-217

Open Data