Table 3 |
||||||||||
|
Relative risks for birth order and age at diagnosis |
||||||||||
|
Age at diagnosis < 50 years |
Age at diagnosis ≥ 50 years |
All |
||||||||
|
Birth order |
Ref |
Birth order |
Ref |
Birth order |
Ref |
|||||
|
Cancer site |
(ICD-7 code) |
N |
RR (95% CI) |
N |
N |
RR (95% CI) |
N |
N |
RR (95% CI) |
N |
|
|
||||||||||
|
Upper aero-digestive tract |
(140+) |
402 |
0.95 (0.82-1.09) |
396 |
577 |
1.09 (0.98-1.21) |
807 |
979 |
1.04 (0.95-1.14) |
1203 |
|
|
||||||||||
|
Salivary glands |
(142) |
119 |
0.79 (0.63-0.99) |
141 |
59 |
0.93 (0.65-1.33) |
96 |
178 |
0.85 (0.70-1.04) |
237 |
|
|
||||||||||
|
Esophagus |
(150) |
55 |
0.89 (0.59-1.37) |
52 |
248 |
0.89 (0.75-1.05) |
435 |
303 |
0.89 (0.76-1.05) |
487 |
|
|
||||||||||
|
Stomach |
(151) |
261 |
1.03 (0.84-1.26) |
232 |
505 |
1.07 (0.95-1.19) |
757 |
766 |
1.06 (0.94-1.20) |
989 |
|
|
||||||||||
|
Small intestine |
(152) |
84 |
0.94 (0.71-1.24) |
85 |
147 |
1.12 (0.92-1.36) |
206 |
231 |
1.07 (0.91-1.26) |
291 |
|
|
||||||||||
|
Colon |
(153) |
938 |
0.94 (0.85-1.04) |
928 |
1532 |
0.97 (0.91-1.04) |
2723 |
2470 |
0.97 (0.91-1.02) |
3651 |
|
|
||||||||||
|
Rectum |
(154/1541) |
376 |
1.03 (0.85-1.26) |
343 |
1084 |
1.03 (0.96-1.11) |
1740 |
1460 |
1.03 (0.95-1.12) |
2083 |
|
|
||||||||||
|
Anus |
(1541) |
66 |
1.08 (0.77-1.50) |
56 |
85 |
0.95 (0.74-1.24) |
133 |
151 |
1.02 (0.83-1.24) |
189 |
|
|
||||||||||
|
Liver and gallbladder |
(155, 156) |
217 |
0.95 (0.80-1.14) |
202 |
467 |
0.92 (0.82-1.04) |
807 |
684 |
0.94 (0.85-1.04) |
1009 |
|
|
||||||||||
|
Pancreas |
(157) |
134 |
0.88 (0.69-1.12) |
128 |
573 |
0.93 (0.81-1.07) |
972 |
707 |
0.93 (0.84-1.03) |
1100 |
|
|
||||||||||
|
Nose |
(160) |
49 |
0.99 (0.64-1.52) |
46 |
47 |
1.19 (0.85-1.67) |
67 |
96 |
1.05 (0.76-1.45) |
113 |
|
|
||||||||||
|
Larynx |
(161) |
58 |
0.82 (0.61-1.10) |
71 |
153 |
1.05 (0.83-1.32) |
227 |
211 |
1.00 (0.83-1.19) |
298 |
|
|
||||||||||
|
Lung |
(162, 163) |
589 |
1.17 (1.04-1.31) |
454 |
2201 |
1.03 (0.97-1.09) |
3343 |
2790 |
1.08 (1.02-1.13) |
3797 |
|
|
||||||||||
|
Breast |
(170) |
5053 |
1.03 (0.82-1.28) |
4778 |
5937 |
0.98 (0.95-1.01) |
8751 |
10990 |
1.00 (0.91-1.11) |
13529 |
|
|
||||||||||
|
Cervix |
(171) |
1609 |
0.95 (0.85-1.06) |
1597 |
245 |
0.83 (0.71-0.97) |
401 |
1854 |
0.93 (0.85-1.02) |
1998 |
|
|
||||||||||
|
Endometrium |
(172) |
213 |
0.72 (0.64-0.81) |
1042 |
321 |
0.87 (0.83-0.92) |
1924 |
1255 |
0.85 (0.81-0.90) |
2245 |
|
|
||||||||||
|
Uterus |
(173, 174) |
140 |
0.91 (0.79-1.04) |
151 |
106 |
0.99 (0.82-1.19) |
166 |
246 |
0.95 (0.85-1.06) |
317 |
|
|
||||||||||
|
Ovary |
(175) |
902 |
0.98 (0.88-1.08) |
868 |
806 |
1.03 (0.95-1.13) |
1177 |
1708 |
1.01 (0.94-1.09) |
2045 |
|
|
||||||||||
|
Other female genital |
(176) |
128 |
1.34 (1.09-1.64) |
90 |
101 |
1.03 (0.85-1.26) |
138 |
229 |
1.20 (1.04-1.38) |
228 |
|
|
||||||||||
|
Prostate |
(177) |
92 |
1.04 (0.83-1.31) |
76 |
4552 |
1.03 (1.00-1.06) |
7984 |
4644 |
1.03 (1.00-1.06) |
8060 |
|
|
||||||||||
|
Testis |
(178) |
1668 |
0.90 (0.84-0.97) |
1582 |
65 |
0.78 (0.60-1.02) |
112 |
1733 |
0.89 (0.83-0.95) |
1694 |
|
|
||||||||||
|
Other male genital |
(179) |
71 |
1.15 (0.94-1.42) |
60 |
81 |
1.22 (1.00-1.48) |
98 |
152 |
1.20 (1.05-1.38) |
158 |
|
|
||||||||||
|
Kidney |
(180) |
663 |
1.00 (0.90-1.10) |
608 |
716 |
0.99 (0.89-1.10) |
1184 |
1379 |
0.99 (0.92-1.06) |
1792 |
|
|
||||||||||
|
Urinary bladder |
(181) |
489 |
1.02 (0.90-1.16) |
486 |
1082 |
0.94 (0.88-1.02) |
1964 |
1571 |
0.97 (0.91-1.04) |
2450 |
|
|
||||||||||
|
Melanoma |
(190) |
2789 |
0.88 (0.83-0.95) |
2952 |
1310 |
0.87 (0.81-0.93) |
2232 |
4099 |
0.88 (0.84-0.92) |
5184 |
|
|
||||||||||
|
Squamous cell skin |
(191) |
412 |
0.97 (0.84-1.12) |
405 |
638 |
0.87 (0.79-0.95) |
1309 |
1050 |
0.90 (0.83-0.98) |
1714 |
|
|
||||||||||
|
Eye |
(192) |
297 |
1.04 (0.89-1.22) |
243 |
88 |
0.90 (0.71-1.15) |
146 |
385 |
1.01 (0.88-1.15) |
389 |
|
|
||||||||||
|
Nervous system |
(193) |
3730 |
1.00 (0.95-1.06) |
3214 |
1126 |
0.99 (0.92-1.07) |
1630 |
4856 |
1.01 (0.96-1.06) |
4844 |
|
|
||||||||||
|
Thyroid gland |
(194) |
821 |
0.86 (0.79-0.95) |
894 |
156 |
0.79 (0.64-0.97) |
289 |
977 |
0.85 (0.78-0.92) |
1183 |
|
|
||||||||||
|
Endocrine glands |
(195) |
1013 |
0.99 (0.91-1.09) |
961 |
568 |
0.87 (0.78-0.98) |
952 |
1581 |
0.95 (0.89-1.02) |
1913 |
|
|
||||||||||
|
Bone |
(196) |
500 |
1.06 (0.94-1.20) |
412 |
37 |
1.11 (0.69-1.79) |
47 |
537 |
1.08 (0.95-1.22) |
459 |
|
|
||||||||||
|
Connective tissue |
(197) |
572 |
0.88 (0.78-0.98) |
576 |
161 |
1.00 (0.82-1.21) |
254 |
733 |
0.90 (0.82-0.99) |
830 |
|
|
||||||||||
|
Non-Hodgkin lymphoma |
(200, 202) |
1330 |
1.06 (0.97-1.15) |
1115 |
1029 |
0.99 (0.91-1.08) |
1611 |
2359 |
1.03 (0.97-1.10) |
2726 |
|
|
||||||||||
|
Hodgkin lymphoma |
(201) |
1001 |
0.92 (0.84-1.01) |
947 |
76 |
1.00 (0.75-1.33) |
109 |
1077 |
0.93 (0.85-1.01) |
1056 |
|
|
||||||||||
|
Myeloma |
(203) |
119 |
0.94 (0.74-1.19) |
117 |
332 |
1.04 (0.89-1.21) |
535 |
451 |
1.02 (0.89-1.15) |
652 |
|
|
||||||||||
|
Leukaemia |
(204 - 209) |
2208 |
0.98 (0.90-1.06) |
1910 |
709 |
1.02 (0.93-1.12) |
1117 |
2917 |
1.00 (0.94-1.07) |
3027 |
|
|
||||||||||
|
Other and unspecified sites |
(other) |
406 |
0.91 (0.79-1.04) |
398 |
838 |
0.89 (0.80-0.99) |
1505 |
1244 |
0.91 (0.84-0.98) |
1903 |
|
|
||||||||||
|
Any site |
(any) |
29574 |
0.97 (0.94-0.99) |
27895 |
29479 |
0.96 (0.93-1.00) |
47948 |
59053 |
0.97 (0.95-1.00) |
75843 |
|
|
||||||||||
|
Reference group: first born child. Bold type, 95% CI does not include 1.00. Poisson regression adjusted for age, sex, period, region, socioeconomic status. Ref.: reference, N:number of cases |
||||||||||
|
Bevier et al. BMC Cancer 2011 11:163 doi:10.1186/1471-2407-11-163 |
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