Additional file 1.

Curcumin and FLLL32 downregulated the expression of STAT3 protein without significant inhibition of STAT3 mRNA transcript levels. OSA8 cells were treated with 10 μM curcumin or 10 μM FLLL32 and were collected at 4 and 24 hours after treatment, and real-time PCR for STAT3 mRNA was performed. Bars represent STAT3 relative expression (2^-Delta Ct). Experiments were performed in triplicate and repeated three times. The difference between treatment groups and DMSO control group was analyzed using the Students t test. P values of < 0.05 were considered statistically significant. There was no statistical significance between the treatment groups.

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Fossey et al. BMC Cancer 2011 11:112   doi:10.1186/1471-2407-11-112