Table 2

Marker gene expression in peripheral blood

Positive blood samples (%)


Patients

Panel

CCNE2

MAL2

EMP2

SLC6A8

DKFZ

PPIC

hMAM

EpCAM


rec. BC (N = 31)

80.6

32.3

19.4

32.3

45.2

25.8

19.4

38.7

19.4


BC (N = 21)

28.6

23.8

0

4.8

0

4.8

0

0

5.0


OC (N = 23)

19.0

13.0

4.3

0

0

0

0

0

0


EC (N = 25)

64.0

36.0

20.0

12.0

12.0

8.0

8.0

0

0


CC (N = 25)

44.0

40.0

4.0

4.0

4.0

4.0

0

0

0


Healthy (N = 26)

0

0

0

0

0

0

0

0

0


The percentage of patients with RT-qPCR positive blood samples is shown. RT-qPCR positivity was defined as gene expression beyond the cut-off threshold, which was set for each gene marker at three standard deviations from the mean expression in healthy control blood samples. Positivity in percentage shown for the "panel" (CCNE2, DKFZp762E1312, EMP2, MAL2, PPIC and SLC6A8) is defined as positivity for at least one of the markers.

(BC: breast cancer, rec. BC: recurrent breast cancer, OC: ovarian cancer, EC: endometrial cancer, CC: cervical cancer, ND: not done)

Obermayr et al. BMC Cancer 2010 10:666   doi:10.1186/1471-2407-10-666

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