Identification of the MLH1, c.454-?_545+?del by MLPA and its breakpoint analysis. The electrophoregram of the index proband of 263CRC family in comparison to a control sample is depicted. The two-fold decrease in height of the peak corresponding to exon 6 of the MLH1 gene is indicated by the green arrows.
Thodi et al. BMC Cancer 2010 10:544 doi:10.1186/1471-2407-10-544