Table 2

Immunostaining of HAS1, HAS2 and HAS3 in human endometrium and its lesions

HAS1

staining

intensity*

HAS2

staining

intensity*

HAS3

staining

intensity*

Epithelium

Stroma

Epithelium

Stroma

Epithelium

Stroma


n.d.

weak

moderate

n.d.

weak

n.d.

weak

moderate

n.d.

weak

n.d.

weak

moderate

n.d.

weak

Normal n = 10

4

2 (10-25%)

4 (10-50%)

7

3 (5-50%)

7

3 (5-10%)

0

8

2 (25%)

5

5 (10-20%)

0

9

1(10%)

Proliferating pmn = 5

5

0

0

5

0

5

0

0

1

4 (5%)

5

0

0

5

0

Hyperplasia # n = 4

1

3 (5-25%)

0

3

1 (10%)

1

2 (10-25%)

1 (50%)

3

1 (10%)

2

2 (10%)

0

3

1(25%)

Grade 1 n = 8

0

5 (5-50%)

3 (25-50%)

6

2 (5%)

2

5 (5-25)

1 (50%)

8

0

3

3 (5-25%)

2 (25-50%)

8

0

Grade 2 + 3 n = 8

0

2 (25-50%)

6 (5-50%)

8

0

0

5 (5-50%)

3 (5-50)

7

1 (5%)

0

3 (10-20%)

5 (10-25%)

8

0


* num. of samples with % of positive cells (% in median; range when necessary)

n.d. = not detected/negative

# complex atypical hyperplasia

pm = post-menopausal

‡ endometrioid endometrial adenocarcinoma

Nykopp et al. BMC Cancer 2010 10:512   doi:10.1186/1471-2407-10-512

Open Data