Research article
Mass spectrometry protein expression profiles in colorectal cancer tissue associated with clinico-pathological features of disease
-
* Corresponding author: John D Norton jnorton@essex.ac.uk
1 Department of Biological Sciences, University of Essex, Wivenhoe Park, Colchester, Essex CO4 3SQ UK
2 ICENI Centre, Department of Surgery, Colchester Hospital University NHS Foundation Trust, Turner Road, Colchester, Essex CO4 5JL UK
BMC Cancer 2010, 10:410 doi:10.1186/1471-2407-10-410
Published: 6 August 2010Additional files
Additional file 1:
Examples of raw MALDI-TOF spectral profiles. Illustrative examples shown for 2012NM and 020T
Format: PDF Size: 36KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional file 2:
Summary of marker peaks discriminating tumour from normal mucosa. Compilation of m/z values, ranking and statistics for 73 marker peaks.
Format: PDF Size: 70KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional file 3:
Performance of predictive model for discriminating tumour and normal mucosa. Summary of results of optimised k-NN algorithm on an independent test dataset.
Format: PDF Size: 29KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional file 4:
Performance of model for predicting poor differentiation based on tumour spectra. Summary of results of 'leave-one-out' cross-validation k-NN algorithm.
Format: PDF Size: 57KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional file 5:
Performance of model for predicting disease recurrence based on tumour spectra. Summary of results of 'leave-one-out' cross-validation k-NN algorithm.
Format: PDF Size: 56KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional file 6:
Performance of model for predicting lymph node involvement based on mucosa spectra. Summary of results of 'leave-one-out' cross-validation k-NN algorithm.
Format: PDF Size: 58KB Download file
This file can be viewed with: Adobe Acrobat Reader