Table 2

HR for death in intention-to-treat population (n = 567)--univariable and multivariable analyses

Univariable analyses

Multivariable analyses


HR (95% CI)

p*

HR (95% CI)

p†

Age (years)

0.033

0.335

≤55

1 (Ref)

1 (Ref)

>55

1.231(1.017-1.490)

0.033

1.224(0.982-1.524)

0.335

Sex

0.816

0.960

Women

1 (Ref)

1 (Ref)

Men

1.025(0.833-1.261)

0.816

0.943(0.748-1.188)

0.960

Tumor size

0.000

0.111

≤5 cm

1 (Ref)

1 (Ref)

5-7 cm

1.527(1.217-1.917)

0.000

1.266(0.991-1.617)

0.059

>7 cm

1.728(1.338-2.233)

0.000

1.397(1.005-1.943)

0.047

Tumour site

0.101

0.005

Upper stomach

1 (Ref)

1 (Ref)

Middle stomach

0.624(0.477-0.816)

0.001

0.585(0.436-0.786)

0.000

Lower stomach

0.626(0.495-0.792)

0.000

0.634(0.482-0.833)

0.001

Whole stomach

1.303(0.889-1.910)

0.174

0.698(0.422-1.154)

0.161

Gross appearance

0.000

0.000

Borrmann types I

1 (Ref)

1 (Ref)

Borrmann types II

1.080(0.824-1.416)

0.576

0.979(0.740-1.294)

0.879

Borrmann types III

1.723(1.364-2.175)

0.000

1.601(1.253-2.046)

0.000

Borrmann types IV

2.141(1.507-3.044)

0.000

1.282(0.841-1.952)

0.248

Tumour stage

0.000

0.651

T1

1 (Ref)

1 (Ref)

T2

0.855(0.638-1.146)

0.295

0.799(0.590-1.082)

0.146

T3

1.262(0.956-1.615)

0.064

0.917(0.698-1.205)

0.535

T4

1.867(1.284-2.716)

0.001

1.005(0.657-1.537)

0.983

Clinical node status

0.372

0.438

Negative

1 (Ref)

1 (Ref)

Positive

1.376(0.683-2.770)

0.372

1.652(0.794-3.436)

0.438

Lymph-node stage

0.000

0.000

N0

1 (Ref)

1 (Ref)

N1

1.342(1.082-1.666)

0.008

1.119(0.863-1.450)

0.397

N2

1.480(1.099-1.994)

0.010

1.238(0.889-1.725)

0.206

N3

3.603(2.497-5.199)

0.000

2.653(1.684-4.179)

0.000

Histological type(%)

0.221

0.556

Differentiated

1 (Ref)

1 (Ref)

Undifferentiated

1.177(0.591-1.529)

0.221

0.897(0.624-1.289)

0.556

Joint organ removal

0.000

0.000

None

1 (Ref)

1 (Ref)

Pancreas or spleen

1.964(1.374-2.808)

0.000

1.364(0.902-2.062)

0.141

Liver or gall

1.380(0.896-2.125)

0.144

1.291(0.823-2.023)

0.266

Transverse colon

1.882(1.321-2.681)

0.000

1.446(0.984-2.125)

0.060

Gastrectomy

0.000

0.001

Total

1 (Ref)

1 (Ref)

Subtotal

0.549(0.422-0.714)

0.000

0.833(0.563-1.233)

0.001

Blood transfusion

0.356

0.580

No

1 (Ref)

1 (Ref)

Yes

1.094(0.904-1.324)

0.356

1.003(0.815-1.234)

0.580

Blood loss

0.789

0.199

≤200 ml

1 (Ref)

1 (Ref)

200-400 ml

0.901(0.723-1.122)

0.350

0.900(0.715-1.134)

0.373

>400 ml

1.049(0.816-1.347)

0.710

0.736(0.552-0.980)

0.036

Lymph node dissection

0.004

0.045

D1

1 (Ref)

1 (Ref)

D2

1.019(0.815-1.275)

0.869

1.024(0.801-1.308)

0.851

D3

0.708(0.560-0.894)

0.004

0.771(0.599-0.992)

0.043


Ref = reference category.

*Derived from tests of HR for prognostic factors in univariate model adjusted for treatment group in Cox proportional-hazards model.

†Cox-regression analysis, controlling for prognostic factors listed in table.

Zhang et al. BMC Cancer 2010 10:308   doi:10.1186/1471-2407-10-308

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