Table 2

Number of cancer cases among subjects that subsequently became digitoxin users.

ICD-10
Site
Sex
Digitoxin group
Control group
Odds Ratio (95% CI)

C50
Breast
F
275
232
1.19(1.11, 1.28)
C61
Prostate
M
370
296
1.25(1.08, 1.45)
C18–21
Colo-rectal
M+F
430
325
1.32(1.15, 1.52)
C32–34
Lung
M+F
163
112
1.46(1.15, 1.86)
C64,C65,C67,C68
Kidney, urinary
M+F
201
180
1.06(0.95, 1.17)
C43.C44
Melanoma, other skin
M+F
154
191
0.81 (0.66, 0.99)
C81–C85,C88–
Leukemia/Lymphoma
M+F
198
117
1.69(1.35,2.11)
C92





C00–C97
All sites
M+F
2435
2017
1.21 (1.15, 1.28)

Number of cancer cases among subjects that subsequently became digitoxin users,and among matched controls.Digitoxin group=the cancer cases among the 9271 patients constituting the database just before the start on digitoxin medication. Control group=for each subject in the digitoxin group one control was randomly picked out from the general population. These controls were matched on birthday and gender and should be alive at the time when the corresponding digitoxin user started on digitoxin.

Haux et al. BMC Cancer 2001 1:11   doi:10.1186/1471-2407-1-11