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Editor-in-Chief Melissa Norton, MD
Medical Editor Jigisha Patel, MRCP PhD
In-house Editor Rachel Neilan MSc
Welcome to BMC Cancer published by BioMed Central
BMC Cancer is an open access journal publishing original peer-reviewed research articles in all aspects of cancer research, including the pathophysiology, prevention, diagnosis and treatment of cancers. The journal welcomes submissions concerning molecular and cellular biology, genetics, epidemiology, and clinical trials.
BMC Cancer (ISSN 1471-2407) is indexed/tracked/covered by PubMed, MEDLINE, CAS, Scopus, EMBASE, Current Contents, Thomson Reuters (ISI) and Google Scholar.
Featured articles
BMC Cancer 2009, 9 :201
The down-regulation of prostasin via the inhibitor protease nexin-1 is associated with the malignant progression of colorectal cancer, indicating that the up-regulation of protease inhibitors may be involved in cancer progression.
BMC Cancer 2009, 9 :128
Zebrafish embryos allow the analysis of tumor cells' circulation, migration and micrometastasis formation in real-time and constitute a simple and sensitive in vivo model for the study of tumor invasion and metastatic behavior.
BMC Cancer 2009, 9 :106
Fluorescence and ultrasound imaging of orthotopic pancreatic tumors in mouse models are potentially a useful combined modality for monitoring tumor growth in real time and thereby enhance the utility of these models for pre-clinical drug testing.
BMC Cancer 2009, 9 :98
An indirect mathematical approach using data from Spain and the US to calculate age- and stage-specific functions for breast cancer survival suggests that increased quality of care and better treatment lead to large improvements in cancer survival in Catalonia.
BMC Cancer 2009, 9 :88
In colorectal cancer patients, circulating levels of cell death markers cytokeratin 18 (CK18) and its caspase-degradation product CK18-Asp396 are predictive of tumor progression and prognosis and may be useful for treatment selection and patient monitoring.
New York, USA. 10 November 2007 BMC Proceedings 2008,
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Research article
The potential biomarkers in predicting pathologic response of breast cancer to three different chemotherapy regimens Linbo Wang, Zhinong Jiang, Meihua Sui, Jianguo Shen, Chaoyang Xu, Weimin Fan BMC Cancer 2009, 9 :226 (11 [Abstract ] [Provisional PDF ]
Review
Molecular fingerprinting of radiation resistant tumors: Can we apprehend and rehabilitate the suspects? Charles J. Rosser, Micah Gaar, Stacy Porvasnik BMC Cancer 2009, 9 :225 (9 [Abstract ] [Provisional PDF ]
Research article
Downregulation of SFRP5 expression and its inverse correlation with those of MMP-7 and MT1-MMP in gastric cancer Chenghai Zhao, Xianmin Bu, Ning Zhang, Wei Wang BMC Cancer 2009, 9 :224 (9 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Integrin alpha6B beta4 inhibits colon cancer cell proliferation and c-Myc activity Anders BONDO Dydensborg, Inga C Teller, Jean-Francois Groulx, Nuria Basora, Frederic Pare, Elizabeth Herring, Remy Gauthier, Dominique Jean, Jean-Francois Beaulieu BMC Cancer 2009, 9 :223 (9 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Health - related quality of life of Kuwaiti women with breast cancer: a comparative study using the EORTC Quality of Life Questionnaire. Shafika A Alawadi, Jude U Ohaeri BMC Cancer 2009, 9 :222 (8 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
CD133 antigen expression in ovarian cancer Gabriella Ferrandina, Enrica Martinelli, Marco Petrillo, Maria Grazia Prisco, Gianfranco Zannoni, Stefano Sioletic, Giovanni Scambia BMC Cancer 2009, 9 :221 (7 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Neuropilin-2 expression in breast cancer: correlation with lymph node metastasis, poor prognosis, and regulation of CXCR4 expression Hironao Yasuoka, Rieko Kodama, Masahiko Tsujimoto, Katsuhide Yoshidome, Hiroki Akamatsu, Masaaki Nakahara, Michiya Inagaki, Tokio Sanke, Yasushi Nakamura BMC Cancer 2009, 9 :220 (7 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Database
DDEC: Dragon database of genes implicated in esophageal cancer Magbubah Essack, Aleksandar Radovanovic, Ulf Schaefer, Sebastian Schmeier, Sundararajan V Seshadri, Alan Christoffels, Mandeep Kaur, Vladimir B Bajic BMC Cancer 2009, 9 :219 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Response of the primary tumor in symptomatic and asymptomatic stage IV colorectal cancer to combined interventional endoscopy and palliative chemotherapy Silke Cameron, Diana Huenerbein, Tuemen Mansuroglu, Thomas Armbrust, Jens-Gerd Scharf, Harald Schwoerer, Laszlo Fuezesi, Giuliano Ramadori BMC Cancer 2009, 9 :218 (1 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer
Jurgen Veeck, Peter J Wild, Thomas Fuchs, Peter J Schuffler, Arndt Hartmann, Ruth Knuchel, Edgar Dahl BMC Cancer 2009, 9 :217 (1 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
In vitro and in vivo antitumor effects of acetylshikonin isolated from Arnebia euchroma (Royle) Johnst (Ruanzicao) cell suspension cultures Wenbi Xiong, Gang Luo, Liming Zhou, Yun Zeng, Wenji Yang Chinese Medicine 2009, 4 :14 (11 [Abstract ] [Provisional PDF ]
Research
Concurrent chemo-radiotherapy following neoadjuvant chemotherapy in locally advanced breast cancer Alberto Alvarado-Miranda, Oscar Arrieta, Carlos Gamboa-Vignolle, David Saavedra-Perez, Rafael Morales-Barrera, Enrique Bargallo-Rocha, Juan Zinser-Sierra, Victor Perez-Sanchez, Teresa Ramirez-Ugalde, Fernando Lara-Medina Radiation Oncology 2009, 4 :24 (11 [Abstract ] [Provisional PDF ]
Research
Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations Ramon Kaneno, Galina V Shurin, Irina L Tourkova, Michael R Shurin Journal of Translational Medicine 2009, 7 :58 (10 [Abstract ] [Provisional PDF ]
Research
Negligible or weak expression of cyclooxygenase-2 is associated with poorer outcome in endemic nasopharyngeal carcinoma: analysis of data from randomized trial between radiation alone versus concurrent chemo-radiation (SQNP-01) Susan Li Er Loong, Jacqueline Siok Gek Hwang, Hui Hua Li, Joseph Tien Seng Wee, Swee Peng Yap, Melvin Lee Kiang Chua, Kam Weng Fong, Terence Wee Kiat Tan Radiation Oncology 2009, 4 :23 (10 [Abstract ] [Provisional PDF ]
Research
Implications of a high-definition multileaf collimator (HD-MLC) on treatment planning techniques for stereotactic body radiation therapy (SBRT): a planning study James A Tanyi, Paige A Summers, Charles L McCracken, Yiyi Chen, Li-Chung Ku, Martin Fuss Radiation Oncology 2009, 4 :22 (10 [Abstract ] [Provisional PDF ]
Research
Influence of the dual ABCB1 and ABCG2 inhibitor tariquidar on the disposition of oral imatinib in mice Erin R Gardner, Nicola F Smith, William D Figg, Alex Sparreboom Journal of Experimental & Clinical Cancer Research 2009, 28 :99 (10 [Abstract ] [Provisional PDF ]
Research
Radiation-induced cancer after radiotherapy for non-Hodgkin's lymphoma of the head and neck: a retrospective study Kazuma Toda, Hitoshi Shibuya, Keiji Hayashi, Fumio Ayukawa Radiation Oncology 2009, 4 :21 (10 [Abstract ] [Provisional PDF ]
Research article
Alternative use of multiple exons 1 of aromatase gene in cancerous and normal breast tissues from women over the age of 80 years Naoko Honma, Kaiyo Takubo, Motoji Sawabe, Tomio Arai, Futoshi Akiyama, Goi Sakamoto, Toshiaki Utsumi, Noriko Yoshimura, Nobuhiro Harada Breast Cancer Research 2009, 11 :R48 (10 [Abstract ] [Provisional PDF ]
Research article
Genomic profiling of breast tumours in relation to BRCA abnormalities and phenotypes Olafur Andri Stefansson, Jon Gunnlaugur Jonasson, Oskar Thor Johannsson, Kristrun Olafsdottir, Margret Steinarsdottir, Sigridur Valgeirsdottir, Jorunn Erla Eyfjord Breast Cancer Research 2009, 11 :R47 (9 [Abstract ] [Provisional PDF ]
Review
Current role of surgery in small cell lung carcinoma Efstratios N Koletsis, Christos Prokakis, Menelaos Karanikolas, Efstratios Apostolakis, Dimitrios Dougenis Journal of Cardiothoracic Surgery 2009, 4 :30 (9 [Abstract ] [Provisional PDF ]
Featured articles 
