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Subject characteristics at time of enrolment |
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| Prenatal multivitamin groups, differing in iron content |
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| 60 mg iron group n = 75 |
35 mg iron group n = 92 |
Total N = 167 |
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| Study inclusion: |
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| a) Had not started multivitamin in current pregnancy |
27 (36%) |
28 (30%) |
55 (33%) |
| b) Had discontinued multivitamin in current pregnancy |
48 (64%) |
64 (70%) |
112 (67%) |
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| Reasons for (a) or (b): |
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| Nausea and/or vomiting (NVP) |
62 (83%) |
68 (74%) |
130 (78%) |
| Tablet sizeψ, swallowing difficulties, other tablet properties (i.e. taste, smell) |
33 (44%) |
20 (22%) |
53 (32%) |
| Constipationβ |
4 (5%) |
14 (15%) |
18 (11%) |
| Abdominal pain, GI irritability, diarrhea, heartburn, reflux |
10 (13%) |
13 (14%) |
23 (14%) |
| GI medical condition (i.e. IBS, Crohn's disease) |
2 (3%) |
2 (2%) |
4 (2%) |
| Doctor's advice, not supplement taker, or lacked information |
5 (7%) |
6 (7%) |
11 (7%) |
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| Maternal age (years) Mean ± standard deviation |
30 ± 5 |
31 ± 5 |
31 ± 5 |
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| Gravidity: |
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| First pregnancy |
23 (31%) |
20 (22%) |
43 (26%) |
| Second or higher pregnancy |
52 (69%) |
72 (78%) |
124 (74%) |
| Multivitamin intake in a previous pregnancy* |
45/52 (87%) |
59/72 (82%) |
104/124 (84%) |
| Discontinued multivitamin in a previous pregnancy* |
26/45 (58%) |
28/59 (47%) |
54/104 (52%) |
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*Data missing for 1 subject. ψ For the subjects who reported issues with tablet size as the reason for non-adherence with previous multivitamins, 22/33 (66%) in the '60 mg' group and 13/20 (65%) in the '35 mg' group still commenced supplementation with the assigned multivitamins. β For the subjects who reported constipation as the reason for non-adherence with previous multivitamins, 2/4 (50%) in the '60 mg' group and 12/14 (86%) in the '35 mg' group still commenced supplementation with the assigned multivitamins. | |||
Nguyen et al. BMC Pregnancy and Childbirth 2008 8:17 doi:10.1186/1471-2393-8-17 |
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