Email updates

Keep up to date with the latest news and content from BMC Pregnancy and Childbirth and BioMed Central.

Open Access Research article

Severe respiratory distress in term infants born electively at high altitude

Ahmad F Bakr* and Mohammad M Abbas

BMC Pregnancy and Childbirth 2006, 6:4  doi:10.1186/1471-2393-6-4

PubMed Commons is an experimental system of commenting on PubMed abstracts, introduced in October 2013. Comments are displayed on the abstract page, but during the initial closed pilot, only registered users can read or post comments. Any researcher who is listed as an author of an article indexed by PubMed is entitled to participate in the pilot. If you would like to participate and need an invitation, please email info@biomedcentral.com, giving the PubMed ID of an article on which you are an author. For more information, see the PubMed Commons FAQ.

Odds Ratio (OR) Measure

MOHAMMED AL-HINDI   (2006-03-03 15:04)  University of Calgary email

Thank you for this interesting article.

I just want to make sure about the OR calculation.

In the abstract and the full text it is mentioned that "Seven of the affected infants were delivered at 37-38 weeks (5.2/1000 births OR = 26, 95%CI -4.6 to 5.8). Five patients delivered at 38 -39 weeks, (2/1000 births) OR = 10 95%CI -4.9 to 5.4)". And then you confirmed that by saying "we found that infants born at 37 and 38 weeks' gestation experience a 26-fold and 10-fold increased risk of severe RDS, respectively". My understanding is that the measure of association, (OR) in this article, should be within the 95% Confidence Interval (CI). The CI of an OR should not be less than zero.

I did some calculations using statistical program (STATA) OR were 25.2(95%CI 3.2-1136) and 9.7 (95%CI 1.08-459, respectively. These CI are so wide, so I recommend to use the Risk Ratio (RR), since its a prospective cohort study, which will give you the following RR 4 (95%CI 3-5.2) and 2.4 (95%CI 3-5.2), respectively.

Please let me know your comments.

Regards

Competing interests

None declared

top

Post a comment