Table 4 

Laboratory data (geometric mean and 95% confidence interval) for senior participants (age 65 years or over) between Phase I and Phase II 

Characteristic 
Phase I 
Phase II 
P value ^{‡} 


Total participants (n) 
202 
186 

Serum folate (nmol/L) 
14.8 (14.0 – 15.6) 
23.0 (22.0 – 24.1) 
<0.001 
RBC folate (mol/L) 
745 (713 – 779) 
916 (873 – 961)^{†} 
<0.001 
Plasma HCY (μmol/L) 
13.6 (13.0 – 14.2)^{†} 
12.3 (11.7 – 12.9)^{†} 
0.001 
Serum vitamin B_{12 }(pmol/L) 
183 (173 – 194) 
216 (202 – 231) 
<0.001 
Plasma MMA (μmol/L) 
0.24 (0.22 – 0.27)^{†} 
0.26 (0.24 – 0.28) 
0.229 


† The KomogorovSmirnov test showed that the log transformed data were nonnormal (p < 0.05). ‡ P value for the difference between Phase I and Phase II is based on a nonparametric MannWhitney U test. RBC denotes red blood cell, HCY denotes homocysteine and MMA refers to methylmalonic acid. 

Liu et al. BMC Pregnancy and Childbirth 2004 4:20 doi:10.1186/14712393420 