Table 4

Laboratory data (geometric mean and 95% confidence interval) for senior participants (age 65 years or over) between Phase I and Phase II

Characteristic

Phase I

Phase II

P value


Total participants (n)

202

186

Serum folate (nmol/L)

14.8 (14.0 – 15.6)

23.0 (22.0 – 24.1)

<0.001

RBC folate (mol/L)

745 (713 – 779)

916 (873 – 961)

<0.001

Plasma HCY (μmol/L)

13.6 (13.0 – 14.2)

12.3 (11.7 – 12.9)

0.001

Serum vitamin B12 (pmol/L)

183 (173 – 194)

216 (202 – 231)

<0.001

Plasma MMA (μmol/L)

0.24 (0.22 – 0.27)

0.26 (0.24 – 0.28)

0.229


† The Komogorov-Smirnov test showed that the log transformed data were non-normal (p < 0.05).

‡ P value for the difference between Phase I and Phase II is based on a non-parametric Mann-Whitney U test.

RBC denotes red blood cell, HCY denotes homocysteine and MMA refers to methylmalonic acid.

Liu et al. BMC Pregnancy and Childbirth 2004 4:20   doi:10.1186/1471-2393-4-20

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