Table 4 |
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|
Laboratory data (geometric mean and 95% confidence interval) for senior participants (age 65 years or over) between Phase I and Phase II |
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|
Characteristic |
Phase I |
Phase II |
P value ‡ |
|
|
|||
|
Total participants (n) |
202 |
186 |
|
|
Serum folate (nmol/L) |
14.8 (14.0 – 15.6) |
23.0 (22.0 – 24.1) |
<0.001 |
|
RBC folate (mol/L) |
745 (713 – 779) |
916 (873 – 961)† |
<0.001 |
|
Plasma HCY (μmol/L) |
13.6 (13.0 – 14.2)† |
12.3 (11.7 – 12.9)† |
0.001 |
|
Serum vitamin B12 (pmol/L) |
183 (173 – 194) |
216 (202 – 231) |
<0.001 |
|
Plasma MMA (μmol/L) |
0.24 (0.22 – 0.27)† |
0.26 (0.24 – 0.28) |
0.229 |
|
|
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|
† The Komogorov-Smirnov test showed that the log transformed data were non-normal (p < 0.05). ‡ P value for the difference between Phase I and Phase II is based on a non-parametric Mann-Whitney U test. RBC denotes red blood cell, HCY denotes homocysteine and MMA refers to methylmalonic acid. |
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|
Liu et al. BMC Pregnancy and Childbirth 2004 4:20 doi:10.1186/1471-2393-4-20 |
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