Table 2 |
||||
|
Indicators of chorioamnionitis: clinical, histologic and microbiological |
||||
|
Cases |
Sub-Cohort |
Relative risk (95% Confidence Intervals) |
P value |
|
|
|
||||
|
Clinical indicators |
n = 82 |
n = 207 |
||
|
Recorded clinical chorioamnionitis |
10 (12%) |
27 (13%) |
0.94 [0.54, 1.64] |
0.84 |
|
Maternal fevera |
21 (26%) |
40 (19%) |
1.26 [0.84, 1.87] |
0.26 |
|
Uterine tenderness |
13 (16%) |
30 (14%) |
1.13 [0.69, 1.82] |
0.63 |
|
Maternal tachycardia |
15 (18%) |
49 (24%) |
0.78 [0.48, 1.26] |
0.31 |
|
Fetal tachycardia |
11 (13%) |
33 (16%) |
0.87 [0.51, 1.49] |
0.62 |
|
Elevated maternal C-reactive protein (>6 mg/L) /no. tested |
29 /38 (76%) |
49 /78 (63%) |
1.75 [0.93, 3.30] |
0.08 |
|
Abnormal maternal whiteblood count >15,000 × 106/L/no. tested |
55 /70 (79%) |
114 /159 (72%) |
1.37 [0.85, 2.23] |
0.20 |
|
Neonatal sepsis |
18 (22%) |
30 (14%) |
1.45 [0.97, 2.18] |
0.07 |
|
Placental Microbiology |
n = 30 |
n = 85 |
||
|
One or more isolates |
11(37%) |
30 (35%) |
1.05 [0.56, 1.96] |
0.88 |
|
Group B Streptococcus |
4 (13%) |
5 (6%) |
1.85 [0.86, 3.97] |
0.12 |
|
Escherichia coli |
6 (20%) |
4 (5%) |
2.35 [1.27, 4.34] |
0.01 |
|
Bacteroides/Prevotella spp. |
3 (10%) |
5 (6%) |
1.54 [0.62, 3.84] |
0.35 |
|
Ureaplasma spp. |
3 (10%) |
14 (16%) |
0.66 [0.23, 1.90] |
0.44 |
|
Other isolates |
4 (13%) |
15 (18%) |
0.79 [0.32, 1.97] |
0.61 |
|
Placental histopathology |
||||
|
Chorioamnionitis |
n = 54 |
n = 150 |
||
|
22 (41%) |
56 (37%) |
1.19 [0.76, 1.88) |
0.45 |
|
|
Funisitis |
n = 54 |
n = 144 |
||
|
14 (26%) |
31 (22%) |
1.35 [0.83, 2.21] |
0.23 |
|
|
|
||||
|
a >37.5°C on two consecutive occasions |
||||
|
Vigneswaran et al. BMC Pregnancy and Childbirth 2004 4:1 doi:10.1186/1471-2393-4-1 |
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