Table 4 |
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|
Risk of adverse perinatal outcomes in relation to alcohol intake peri-conceptionally |
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|
Alcohol intakei |
Low (0 - 5 units) Unadjusted OR (95% CI) |
Low (0-5 units) Adjusted ORii (95% CI) |
Moderate (6 - 20 units) Unadjusted OR (95% CI) |
Moderate (6-20 units) Adjusted ORii (95% CI) |
High (>20 units) Unadjusted OR (95% CI) |
High (>20 units) Adjusted ORii (95% CI) |
|
|
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|
Preterm birth <37 weeks |
0.72 (0.66-0.78) |
0.77 (0.69-0.85) |
0.70 (0.61-0.81) |
0.71 (0.60-0.83) |
1.70 (0.55-3.05) |
1.00 (0.53-1.87) |
|
Very preterm birth <32 wks |
0.76 (0.63-0.92) |
0.88 (0.70-1.11) |
0.82 (0.61-1.10) |
0.95 (0.66-1.37) |
3.93 (1.70-9.06)* |
3.15 (1.26-7.88)* |
|
Low birth weight <2500 g |
0.75 (0.69-0.83) |
0.69 (0.61-0.78) |
0.82 (0.71-0.95) |
0.71 (0.58-0.87) |
2.09 (1.14-3.83)* |
1.15 (0.60-2.22) |
|
Birth weight <10th centile |
0.97 (0.92-1.03) |
1.01 (0.96-1.06) |
1.06 (0.98-1.17) |
1.00 (0.92-1.09) |
2.82 (1.88-4.23)* |
1.44 (0.91-2.25) |
|
Perinatal death |
0.86 (0.69-1.08) |
0.65 (0.47-0.90) |
0.93 (0.65-1.32) |
0.72 (0.44-1.18) |
2.11 (0.51-8.65) |
1.56 (0.33-7.44) |
|
Apgar score <7 at 5 minutes |
0.77 (0.64-0.92) |
0.67 (0.53-0.85) |
0.88 (0.66-1.17) |
0.62 (0.42-0.92) |
1.32 (0.32-5.41) |
1.09 (0.25-4.73) |
|
Admission to neonatal unit |
0.89 (0.84-0.95) |
0.84 (0.78-0.90) |
0.95 (0.87-1.03) |
0.83 (0.73-0.93) |
1.37 (0.86-2.17) |
0.91 (0.56-1.49) |
|
Congenital abnormality (any) |
0.85 (0.76-1.24) |
1.01 (0.71-1.44) |
1.01 (0.85-1.21) |
1.01 (0.82-1.27) |
0.81 (0.26-2.56) |
0.56 (0.17-1.88) |
|
|
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|
i Reference category for all comparisons - alcohol intake response "Never" ii adjusted for maternal age, single marital status, socio-economic status, nationality, private health insurance, nulliparity, unplanned pregnancy, late booking, smoking and history of illicit drug use * p < 0.05 |
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|
Mullally et al. BMC Pregnancy and Childbirth 2011 11:27 doi:10.1186/1471-2393-11-27 |
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