Table 2

Antihypertensive therapy among singleton pregnant women with either all forms of hypertension or hypertension before 20 weeks gestation

No. (%)


Drug use

Women with all forms of hypertension (n = 1948)

Women with hypertension before 20 weeks gestation (n = 583)


By number of drugs

None

980 (50.3)

247 (42.4)

Single agent

569 (29.2)

207 (35.5)

Multiple agents

399 (20.5)

129 (22.1)

Total

1948 (100.0)

583 (100.0)

By drug class

i) Beta-blockers*

Atenolol

743 (94.9)

236 (92.9)

Labetolol

29 (3.7)

10 (3.9)

Propranolol

8 (1.0)

6 (2.4)

Acebutalol

3 (0.4)

2 (0.8)

Total

783 (100.0)

254 (100.0)

ii) Non-beta-blockers*

Nifedipine

301 (47.7)

93 (38.9)

Methyldopa

175 (27.7)

91 (38.1)

Hydralazine

129 (20.4)

30 (12.6)

Enalapril or captopril

19 (3.0)

19 (7.9)

Hydrochlorothiazide

5 (0.8)

5 (2.1)

Furosemide

2 (0.3)

1 (0.4)

Total

631 (100.0)

239 (100.0)


*Represents use of that agent either alone or in combination with one or more drugs.

Ray et al. BMC Pregnancy and Childbirth 2001 1:6   doi:10.1186/1471-2393-1-6

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