Table 2 |
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Antihypertensive therapy among singleton pregnant women with either all forms of hypertension or hypertension before 20 weeks gestation |
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No. (%) |
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|
|
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|
Drug use |
Women with all forms of hypertension (n = 1948) |
Women with hypertension before 20 weeks gestation (n = 583) |
|
|
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|
By number of drugs |
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|
None |
980 (50.3) |
247 (42.4) |
|
Single agent |
569 (29.2) |
207 (35.5) |
|
Multiple agents |
399 (20.5) |
129 (22.1) |
|
Total |
1948 (100.0) |
583 (100.0) |
|
By drug class |
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|
i) Beta-blockers* |
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|
Atenolol |
743 (94.9) |
236 (92.9) |
|
Labetolol |
29 (3.7) |
10 (3.9) |
|
Propranolol |
8 (1.0) |
6 (2.4) |
|
Acebutalol |
3 (0.4) |
2 (0.8) |
|
Total |
783 (100.0) |
254 (100.0) |
|
ii) Non-beta-blockers* |
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|
Nifedipine |
301 (47.7) |
93 (38.9) |
|
Methyldopa |
175 (27.7) |
91 (38.1) |
|
Hydralazine |
129 (20.4) |
30 (12.6) |
|
Enalapril or captopril |
19 (3.0) |
19 (7.9) |
|
Hydrochlorothiazide |
5 (0.8) |
5 (2.1) |
|
Furosemide |
2 (0.3) |
1 (0.4) |
|
Total |
631 (100.0) |
239 (100.0) |
|
|
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*Represents use of that agent either alone or in combination with one or more drugs. |
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Ray et al. BMC Pregnancy and Childbirth 2001 1:6 doi:10.1186/1471-2393-1-6 |
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