Table 4

Associations of childhood and adulthood direct pesticide application with PD as divided into chemical classes.



% Exposed*







Functional type
History of pesticide use for each chemical class
Cases, n = 319
Controls, n = 296
OR and 95% CI (GEE model 2)**

Insecticide
Botanical





     Ever
2.2
0.3
5.93
0.63–56.10

     Ever to any other pesticide
60.5
49.3
1.57
1.10–2.24

     Never
37.3
50.3
1.00
Referent

N-Methyl carbamate





     Ever
11.9
10.8
1.31
0.75–2.28

     Ever to any other pesticide
50.8
38.9
1.70
1.17–2.47

     Never
37.3
50.3
1.00
Referent

Organochlorine





     Ever
13.2
7.1
1.99
1.09–3.64

     Ever to any other pesticide
49.5
42.6
1.54
1.07–2.23

     Never
37.3
50.3
1.00
Referent

Organophosphorus





     Ever
16.6
10.1
1.89
1.11–3.25

     Ever to any other pesticide
46.1
39.5
1.53
1.05–2.23

     Never
37.3
50.3
1.00
Referent
Herbicide
Chlorophenoxy acid/ester





     Ever
4.7
2.7
2.07
0.69–6.23

     Ever to any other pesticide
58.0
47.0
1.58
1.11–2.27

     Never
37.3
50.3
1.00
Referent

Phosphonoglycine





     Ever
17.9
13.5
1.53
0.92–2.53

     Ever to any other pesticide
44.8
36.1
1.64
1.12–2.40

     Never
37.3
50.3
1.00
Referent

Triazine





     Ever
1.6
2.4
1.08
0.32–3.59

     Ever to any other pesticide
61.1
47.3
1.63
1.14–2.33

     Never
37.3
50.3
1.00
Referent
Multiple uses
Inorganic/metal





     Ever
5.0
3.0
1.51
0.62–3.71

     Ever to any other pesticide
57.7
46.6
1.61
1.13–2.31

     Never
37.3
50.3
1.00
Referent

*Column totals may not sum to 100 due to rounding or missing data.

**GEE model adjusted for AAE, sex, cigarette smoking, and caffeine consumption.

Hancock et al. BMC Neurology 2008 8:6   doi:10.1186/1471-2377-8-6