Table 1

Characteristics of the different needles studied in the single- and multi-center trials of healthy volunteers

Needle gauge

Number of bevels

Needle shield material

Type of silicone lubricant

Single-center study

Multi-center study


27a

3

Rubber

A

×

××

27

5

TPE

B

×

27

5

Rubber

A

×

27

5

TPE

A

×

×

27

3

Rubber

A

×

29

3

TPE

A

×

29

5

Rubber

A

×

29b

5

TPE

A

×

×

27 disposable needle

-

-

A

×

29 disposable needle

-

-

A

×


IFN, interferon; sc, subcutaneous; tiw, three times weekly; TPE, Thermo Plastic Elastomer.

aNeedle used previously for the injection of IFN β-1a, 44 or 22 mcg sc tiw.

bNeedle used currently for the injection of IFN β-1a, 44 or 22 mcg sc tiw.

Jaber et al. BMC Neurology 2008 8:38   doi:10.1186/1471-2377-8-38

Open Data