Figure 1.

Pedigree diagram showing affection status and disease haplotype. Squares indicate males and circles females; filled arrow indicates proband; black symbols show individuals clinically diagnosed with dementia, either AD or FTLD; diagonal stripes, individuals diagnosed with MND; and combined black and diagonal stripes, individuals diagnosed with FTLD-MND. A diagonal line marks deceased subjects. Individual I:1, lived until his 80s, but was thought to have had some personality changes. Alleles in parentheses are inferred. 'X' indicates upper and lower recombination breakpoints that define the minimal disease haplotype.

Luty et al. BMC Neurology 2008 8:32   doi:10.1186/1471-2377-8-32
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